Sinaga, Rosalinda Mahdalena dan Lubis, Minda Sari dan Dalimunthe, Gabena Indrayani dan Rahayu, Yayuk Putri (2023) Phytochemical Screening, Formulation, and Physical Characteristics Of Soothing Gel Aloe Vera Leaf Flesh (Aloe Vera (L.) Burm.F.) / Skrining Fitokimia, Formulasi, dan Karakteristik Fisik Sediaan Soothing Gel Daging Daun Lidah Buaya (Aloe vera (L.) Burm.f.). Journal of Pharmaceutical and Sciences. hal. 1729-1737.
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The content of aloe vera (Aloe vera (L.) Burm.f.) can make the skin not dry quickly and feel moisturised. Soothing gel is a preparation that works effectively to restore skin moisture, provide comfort and a cooling effect on red and irritated skin so that the skin condition returns to normal and prevents skin dryness. The study aimed to determine the various secondary metabolites in aloe vera leaf flesh, to determine differences in concentrations of aloe vera leaf flesh in soothing gel preparations on the physical characteristics of the practices and to determine material changes before and after stability tests were carried out using the cycling test method. The research method was used experimental, with the independent variables varying the aloe vera leaf flesh concentration 0% (blank), 1%, 2%, and 3%, and the dependent variable secondary metabolites and physical characteristics. The sample preparation method is wet sorting, and other methods used are phytochemical screening, viscometry, and cycling tests. The results of the phytochemical screening showed that aloe vera leaf flesh contains secondary metabolites of flavonoids, glycosides, tannins, saponins, and steroids. The results of the soothing gel formulation with variations in the aloe vera leaf flesh concentration of 0%, 1%, 2%, and 3% showed differences in colour, distinctive aroma, consistency, spreadability, adhesion, pH, and viscosity that met the requirements. The stability test results using the cycling test method showed physical changes in consistency, spreadability, adhesion, pH, and viscosity. However, these changes still met the requirements for good gel preparation according to SNI 16-4399-1996.
Lidah buaya (Aloe vera (L.) Burm.f.) dapat membuat kulit tidak cepat kering dan terasa lembab. Soothing gel bekerja efektif mengembalikan kelembapan kulit, memberi kenyamanan dan kesan mendingin di kulit yang kemerahan dan iritasi sehingga kondisi kulit kembali normal, dan mencegah kekeringan kulit. Tujuan penelitian untuk mengetahui berbagai metabolit sekunder dalam daging daun lidah buaya, mengetahui perbedaan konsentrasi daging daun lidah buaya dalam sediaan soothing gel terhadap karakteristik fisik sediaan dan mengetahui perubahan fisik sebelum dan sesudah dilakukan uji stabilitas menggunakan metode cycling test. Metode penelitian adalah eksperimen, dengan variabel bebas variasi konsentrasi daging daun lidah buaya 0% (blangko), 1%, 2%, dan 3%, variabel terikat metabolit sekunder dan karakteristik fisik. Metode penyiapan sampel yaitu sortasi basah dan metode lainnya skrining fitokimia, viskometri, dan cycling test.Hasil skrining fitokimia yaitu daging daun lidah buaya mengandung metabolit sekunder flavonoid, glikosida, tanin, saponin, dan steroid. Hasil formulasi soothing gel dengan variasi konsentrasi daging daun lidah buaya 0%, 1%, 2%, dan 3% menunjukkan perbedaan warna, aroma khas, konsistensi, daya sebar 5-7 cm, daya lekat lebih dari 4 detik, pH 5,63-6,14, dan viskositas 5.000-21.280 cPs yang memenuhi syarat. Hasil uji stabilitas menggunakan metode cycling test menunjukkan adanya perubahan fisik konsistensi, daya sebar, daya lekat, pH, dan viskositas, tetapi perubahan tersebut masih memenuhi syarat sediaan gel yang baik menurut SNI 16-4399-1996.
| Jenis koleksi: | Artikel jurnal |
|---|---|
| Informasi Tambahan: | OAI: oai:ojs3.journal-jps.com:article/274 Source: https://journal-jps.com/new/index.php/jps/oai Rights: Copyright (c) 2023 Rosalinda Mahdalena Sinaga, Minda Sari Lubis, Gabena Indrayani Dalimunthe, Yayuk Putri Rahayu; https://creativecommons.org/licenses/by-nc-sa/4.0 Bibliographic source: Journal of Pharmaceutical and Sciences; JPS Volume 6 Nomor 4 (2023); 1729-1737; Journal of Pharmaceutical and Sciences; JPS Volume 6 Nomor 4 (2023); 1729-1737; 2656-3088; 10.36490/journal-jps.com.v6i4 |
| Pengguna yang Menyetor: | Pengguna tanpa nama dengan email repo@utnd.ac.id |
| Tanggal Disetor: | 10 Oktober 2026 22:29 |
| Terakhir Dimodifikasi: | 10 Oktober 2026 22:29 |
| URI: | http://utndrepository.utnd.ac.id/id/eprint/821 |

