Rosi, Devahimer Harsep dan Nadifa, Putri dan Farnandi, Rido (2026) Formulation, physical stability, and changes in skin hydration after use of a body scrub cream containing moringa leaf extract (Moringa oleifera) and black glutinous rice (Oryza sativa var. glutinosa) / Formulasi, stabilitas fisik, dan perubahan kelembapan kulit setelah penggunaan krim body scrub ekstrak daun kelor (Moringa oleifera) dan beras ketan hitam (Oryza sativa var. glutinosa). Journal of Pharmaceutical and Sciences. hal. 2944-2954.
Teks lengkap tidak tersedia dari repositori ini.Abstrak
Background: Moringa leaf extract and black glutinous rice are potential ingredients for body scrub formulations. This study evaluated their incorporation into a cream, its physical stability and sensory acceptability, and changes in skin hydration. Methods: Dried moringa leaves were macerated in 96% ethanol. F1, F2, and F3 contained 1, 2, and 3 g of extract, respectively, and 5 g of black glutinous rice powder. F0 was the negative control, and a commercial rice body scrub was the comparator. Physical characteristics were evaluated over four weeks and after three temperature cycles at 4 ± 2 °C and 40 ± 2 °C. Hedonic testing involved 20 panelists; skin hydration, oil, and softness were assessed in five volunteers over four weeks. Results: Extraction yielded 60.73 g (20.24%); alkaloids, flavonoids, saponins, and tannins were detected. During storage, pH ranged from 4.84 to 6.49, spreadability from 4.90 to 6.40 cm, and adhesion from 4.27 to 6.56 s. No visible changes in color, consistency, or odor occurred during temperature cycling. No redness, itching, or swelling was observed within 24 h of the irritation test. F1 had the highest descriptive preference scores for four sensory attributes; aroma differed among formulations in the reported Kruskal–Wallis analysis (p = 0.003). F3 had the largest observed hydration increase among experimental formulations, from 28.8% to 46.2% at week 4 (relative increase, 60.4%); the reported between-group test yielded p = 0.001. Conclusion: The formulations retained their observed physical characteristics under the tested conditions. F1 was preferred in the sensory evaluation, whereas F3 showed the largest observed improvements in hydration and softness. These exploratory findings do not establish comparative clinical efficacy or long-term safety.
Latar belakang: Ekstrak daun kelor dan beras ketan hitam berpotensi digunakan dalam formulasi krim body scrub. Penelitian ini bertujuan mengevaluasi formulasi, stabilitas fisik, penerimaan sensoris, dan perubahan kelembapan kulit setelah penggunaan sediaan. Metode: Serbuk daun kelor dimaserasi menggunakan etanol 96%. F1, F2, dan F3 masing-masing mengandung 1, 2, dan 3 g ekstrak serta 5 g serbuk beras ketan hitam. F0 merupakan kontrol negatif, sedangkan body scrub beras komersial digunakan sebagai pembanding. Karakteristik fisik dievaluasi selama empat minggu dan setelah tiga siklus suhu pada 4 ± 2 °C dan 40 ± 2 °C. Uji hedonik melibatkan 20 panelis; kelembapan, minyak, dan kehalusan kulit dinilai pada lima sukarelawan selama empat minggu. Hasil: Ekstraksi menghasilkan 60,73 g ekstrak (20,24%) dengan hasil positif untuk alkaloid, flavonoid, saponin, dan tanin. Selama penyimpanan, pH berkisar 4,84–6,49, daya sebar 4,90–6,40 cm, dan daya lekat 4,27–6,56 detik. Tidak teramati perubahan warna, bentuk, atau bau setelah siklus suhu. Tidak ditemukan kemerahan, gatal, atau pembengkakan selama pengamatan iritasi 24 jam. F1 memperoleh skor kesukaan deskriptif tertinggi pada empat atribut sensoris; analisis Kruskal–Wallis yang dilaporkan menunjukkan perbedaan aroma antarformula (p = 0,003). F3 menunjukkan peningkatan kelembapan terbesar di antara formula uji, dari 28,8% menjadi 46,2% pada minggu ke-4 (peningkatan relatif 60,4%); uji antarkelompok yang dilaporkan menghasilkan p = 0,001. Kesimpulan: Sediaan mempertahankan karakteristik fisik yang diamati pada kondisi pengujian. F1 lebih disukai secara sensoris, sedangkan F3 menunjukkan peningkatan kelembapan dan kehalusan terbesar secara deskriptif. Temuan eksploratif ini belum membuktikan efektivitas klinis komparatif ataupun keamanan jangka panjang.
| Jenis koleksi: | Artikel jurnal |
|---|---|
| Informasi Tambahan: | OAI: oai:ojs3.journal-jps.com:article/1669 Source: https://journal-jps.com/new/index.php/jps/oai Rights: Copyright (c) 2026 Devahimer Harsep Rosi , Putri Nadifa , Rido Farnandi ; https://creativecommons.org/licenses/by-nc-sa/4.0 Bibliographic source: Journal of Pharmaceutical and Sciences; JPS Volume 9 Nomor 3 (2026); 2944-2954; Journal of Pharmaceutical and Sciences; JPS Volume 9 Nomor 3 (2026); 2944-2954; 2656-3088; 10.36490/journal-jps.com.v9i3 |
| Pengguna yang Menyetor: | Pengguna tanpa nama dengan email repo@utnd.ac.id |
| Tanggal Disetor: | 10 Oktober 2026 22:26 |
| Terakhir Dimodifikasi: | 10 Oktober 2026 22:26 |
| URI: | http://utndrepository.utnd.ac.id/id/eprint/1473 |

