Implementation of Pharmacist Education to Improve Knowledge, Adherence, and Treatment Success in Hyperuricemia Patients in Community Pharmacy / Implementasi Edukasi Apoteker Untuk Meningkatkan Pengetahuan, Kepatuhan Dan Keberhasilan Terapi Pada Pasien Hiperurisemia Di Farmasi Komunitas

Hyperuricemia is a condition characterized by elevated uric acid levels that may lead to gout arthritis and metabolic complications. Therapeutic success is strongly influenced by patients’ knowledge and adherence, highlighting the important role of pharmacist-led education in community pharmacy settings. This study aimed to evaluate the effect of pharmacist education on improving knowledge, medication adherence, and treatment success among hyperuricemia patients. A quasi-experimental pretest–posttest study with a control group was conducted involving 170 patients (85 intervention and 85 control) recruited through consecutive sampling. The intervention group received structured pharmacist education and counseling, while the control group received usual care. Outcomes were assessed at baseline and after a 14-day follow-up period. Patient knowledge was measured using a validated questionnaire, adherence was assessed using the MARS-5, and treatment success was evaluated through changes in pain intensity (VAS), serum uric acid levels, and treatment satisfaction using the TSQM-9.The Wilcoxon and Mann–Whitney U tests showed significant improvements in the intervention group compared to the control group. The intervention group demonstrated increased knowledge (Δ3.37), improved adherence (Δ3.67), greater reduction in uric acid levels (Δ1.25 mg/dL), more substantial pain reduction—particularly in disruptive pain (37% vs 13%)—and higher treatment satisfaction (95.29% vs 62.35%).In conclusion, a short-term pharmacist-led educational intervention with a 14-day follow-up effectively improves knowledge, adherence, and therapeutic outcomes in hyperuricemia patients in community pharmacies, supporting its feasibility for routine implementation.

Hiperurisemia merupakan kondisi meningkatnya kadar asam urat yang berpotensi menyebabkan gout artritis dan berbagai komplikasi metabolik. Keberhasilan terapi sangat dipengaruhi oleh tingkat pengetahuan dan kepatuhan pasien terhadap pengobatan, sehingga edukasi dan konseling oleh apoteker di farmasi komunitas memegang peranan penting dalam meningkatkan pemahaman dan perilaku pasien. Penelitian ini bertujuan menganalisis pengaruh edukasi apoteker terhadap peningkatan pengetahuan, kepatuhan, dan keberhasilan terapi pasien hiperurisemia. Desain penelitian menggunakan quasi-experimental pretest–posttest with control group melibatkan 85 pasien kelompok intervensi dan 85 pasien kelompok kontrol yang dipilih melalui concecutive sampling. Intervensi berupa edukasi dan konseling terstruktur oleh apoteker. Pengukuran pengetahuan dilakukan menggunakan kuesioner tervalidasi, kepatuhan dinilai dengan MARS-5, keberhasilan terapi dinilai melalui tingkat nyeri menggunakan VAS, kadar asam urat, serta kepuasan terapi dengan TSQM-9. Hasil analisis Wilcoxon dan Mann–Whitney U menunjukkan perbedaan signifikan antara kelompok intervensi dan kontrol. Kelompok intervensi mengalami peningkatan pengetahuan (Δ3,37), peningkatan kepatuhan (Δ3,67), penurunan kadar asam urat (Δ1,25), penurunan nyeri lebih besar terutama pada kategori nyeri mengganggu (37% vs 13%), serta tingkat kepuasan terapi pada kelompok intervensi 95,29% menyatakan puas sedangkan kelompok kontrol hanya mencapai 62,35% menyatakan puas. Penelitian ini menyimpulkan bahwa edukasi apoteker secara efektif meningkatkan pengetahuan, kepatuhan, dan keberhasilan terapi pada pasien hiperurisemia di farmasi komunitas.